Endometriosis.

[Mister Obvious]

Hi.

[Mister Obvious]

Just not pleasant at all.

[Mister Obvious]

For anyone who doesn't know...

Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain and other symptoms.

While it can sometimes be mild or even asymptomatic, endometriosis can progress and lead to more severe pain, heavier bleeding, and other complications as it spreads and causes inflammation and scar tissue formation.

Endometriosis can intensify ovulation pain because the inflammation and scar tissue caused by the disease worsen the natural inflammatory process of ovulation.

Endometrial tissue can also grow in other areas, including on blood vessels, the cervix, diaphragm, lungs, nerves, and inside of scars.

[Mister Obvious]

Endometriosis really just gets worse over time and it can continue after hysterectomy and menopause.

It's failed to be recognized as an autoimmune disease, but that's what it is.

During ovulation, endometrial tissue throughout the body acts up due to hormonal fluctuations.

During menstruation, endometrial tissue THROUGHOUT THE BODY "bleeds" just like the lining of the uterus, but because it's NOT IN THE FUCKING UTERUS, it can't get flushed out...

Endometriosis, a condition where tissue similar to the uterine lining grows outside the uterus, can cause internal bleeding. This occurs because the displaced tissue thickens, breaks down, and bleeds during menstruation, but unlike the uterine lining, this blood has no way to exit the body.

So it has to be slowly reabsorbed by the body over time.

[Mister Obvious]

Sugar and processed foods make it worse.

[Mister Obvious]

Endometriosis can make it more difficult to get pregnant. Between 30-50% of people with endometriosis may experience infertility. The normal chance of getting pregnant each month for people with no endometriosis is approximately 10-20%, while people with surgically documented endometriosis have a chance of only 1-10%.

Not that it matters in my personal case.

[Mister Obvious]

[Mister Obvious]

Genetic predisposition to the condition: This theory suggests that endometriosis is passed down to new generations through the genes of family members.

https://www.endometriosis-uk.org/sites/d...pack_0.pdf

It's the gift of life, my bitches...

[Mister Obvious]

Antihistamines show potential as an endometriosis treatment because mast cells in endometrial lesions release histamine, a key inflammatory mediator.

By blocking histamine receptors, antihistamines can help reduce inflammation and symptoms like pain, although this approach is not yet a standard, widely-used treatment. Research into H1-antihistamines suggests they could be used alongside established hormonal therapies to manage endometriosis.

Loratadine is being investigated as a potential endometriosis treatment because it can suppress the growth and migration of endometrial cells by inhibiting the TRPV2 channel.

https://pubmed.ncbi.nlm.nih.gov/35714693

'Bout to pop some loratadine.

[Mister Obvious]

Feels like period cramps, but it's ovulation. Hurts. Stomach is sore to the touch.

[Mister Obvious]

Just aches and aches and aches.

[Mister Obvious]

Radiates, just makes you feel fucking sick.